News
& Notices
Organizations & People
Standing
Committees
Divisions
Projects
..current
..completed
..new
..information
Reports
Publications
Symposia
AMP
Links
of Interest
Search
the Site
Home
Page
|
|
Project
Chemistry
and the Environment Division (VI)
Number: 2003-011-3-600
Title: A critical compendium of
pesticide physical chemistry data
Task Group
Chairmen: R. Don
Wauchope and David
G. Shaw
Members:
Robert Eganhouse,
Zev Gerstl, Forrest
Getzen, Kenneth Racke,
Mark Salomon, and
Jamse Sangster
Completion Date:
Objective:
Establish an IUPAC compendium of critically evaluated values for
aqueous solubility, vapor pressure, octanol/water partition coefficient,
and acid/base dissociation constant (pKa) for active ingredients
of pesticides. Use the procedures and approaches developed by the
IUPAC Solubility Data Project as well as pesticide expertise from
Industry and the former Agrochemical Commission.
Description:
Solubility in water, vapor pressure, octanol/water partition
coefficient, and acid/base dissociation constant (pKa) are basic
properties that may be measured with a known precision for any chemical
substance. These quantities are of considerable practical significance
as they play fundamental roles in describing the pharmacology, toxicology,
and environmental fate and behavior of chemicals, as well as being
basic input parameters for pesticide risk assessment modeling. Remarkably,
few of these parameters have ever been critically evaluated or even
exhaustively compiled for the chemical substances that are active
ingredients of pesticides. A recent report by Pontolillo and Eganhouse
(U.S. Geological Survey Water-Resources Investigations Report 01-4201)
indicates that the literature concerning these properties is fragmented
and tends to perpetuate erroneous values.
We propose an exhaustive compilation and critical evaluation of
these four properties including manufacturer data which may not
have appeared in the primary literature, using methods adapted from
those used by the IUPAC Solubility Data Project (Getzen, Salomon,
Sangster, Shaw and Skrzecz are participants). Our evaluations will
lead to categorization of data as "Recommended", "Tentative",
or "Rejected". Where unpublished data is included this
will be carefully considered in evaluations and clearly identified
for users. As new pesticide active ingredients are added the web/volume
would be updated by later Project(s)
Progress:
Broader membership developed; internet discussion list established.
> Nov 2004 report update (pdf
file - 11KB)
> May 2006 report update (pdf
file - 12KB)
Last update: 19 July 2007
If
you want to update this information, contact us by e-mail
Do not forget to include the Project Number,
your name and relation with that project
Page last modified 19 July 2007.
Copyright ©1997-2007 International Union of Pure and Applied
Chemistry.
Questions or comments about IUPAC, please contact, the Secretariat.
Questions regarding the website, please contact web
manager.
|