I  U  P  A  C






News & Notices

Organizations & People

Standing Committees

Divisions

Projects

Reports

Publications
..CI
..PAC
..Macro. Symp.

..Books
..Solubility Data

Symposia

AMP

Links of Interest

Search the Site

Home Page

 

Pure Appl. Chem., Vol. 72, No. 9, pp. 1649-1653, 2000.

 

 

Fluorous methods for synthesis and separation of organic molecules*

Dennis P. Curran

Department of Chemistry, University of Pittsburgh, Pittsburgh, PA 15260 USA

Abstract: Fluorous molecules partition out of an organic phase and into a fluorous (highly fluorinated) phase in a liquid-liquid extraction. New fluorous techniques allow simple yet substantive separations of organic reaction mixtures based on the presence or absence of a fluorous tag. Fluorous-tagged molecules can also be separated from nontagged molecules by solid phase extraction over fluorous reverse-phase silica gel. This technique is ideal for solution-phase parallel synthesis because it allows simple yet substantive separations of organic reaction mixtures.

*Lecture presented at the 13th International Conference on Organic Synthesis (ICOS-13), Warsaw, Poland, 1-5 July 2000.

Back to Contents for access to full text


Page last modified 15 January 2001.
Copyright ©2000-2001 International Union of Pure and Applied Chemistry.
Questions or comments about IUPAC, please contact, the Secretariat.
Questions regarding the website, please contact web manager.