Synthesis of an analog of mycothiazole and total synthesis of pseudotrienic acid B*
Dominique Amans, Alexandre Le Flohic, Véronique Bellosta, Christophe Meyer, and Janine Cossy
Laboratoire de Chimie Organique Associé au CNRS, ESPCI, 10 rue Vauquelin 75231, Paris Cédex 05, France
Abstract: An analog of mycothiazole and pseudotrienic acid B were synthesized efficiently by using ring-closing metathesis or cross-metathesis as key reactions.
Keywords: natural products; total synthesis; ring-closing metathesis; cross-metathesis; crotyltitanation.
*Pure Appl. Chem. 79, 467-823 (2007) pp. 467-823. An issue of reviews and research papers based on lectures presented at the 25th International Symposium on Chemistry of Natural Products (ISCNP-25) and 5th International Conference on Biodiversity (ICOB-5), held jointly in Kyoto, Japan, 23-28 July 2006, on the theme of natural products.