Main tasks:
1- Update and classification
of the literature (theoretical and experimental) on supplemented
phase diagrams, of relevant aqueous systems for food and pharmaceutical
sciences, from simple binary solutions to complex systems.
2- Comparison of methods
based on measurements at different frequencies to determine
phase/state transitions and to assess the effect of water content
on their temperatures and kinetics.
3- Proposition of
suitable standard procedures to determine glass and enthalpic
(crystallization, melting) transition temperatures in aqueous
systems over a wide water content range.
4- Analysis of empirical
and theoretical models to predict transition temperatures and
of their applicability to the systems under consideration.
5- Optimization of
the use of state diagrams to predict the stability of biomolecules
under different conditions, including pressure effect, multicomponent
systems, etc.
Milestones first year (reformulated):
·
July 2004:
Define scope of work
and responsibilities of each group member.
Start of data base.
·
August 2004:
Create web page restricted
to the Task Group for sharing information.
·
September 2004:
Data base
First Task Group Meeting
in Mar del Plata, Argentina (ISOPOW 9).
·
December 2004:
First internal release
with a critical evaluation of the data base and common theoretical/experimental
shortcomings of current practices.
·
March 2005:
First draft of the
IUPAC Technical Report
Opening of the web
page to the public.
Tentative task distribution (prior to ISOPOW 9 Meeting in
Argentina)